4-(1H-pyrazol-1-yl)benzoic acid

4-(1H-pyrazol-1-yl)benzoic acid - Names and Identifiers

Name	4-(1H-pyrazol-1-yl)benzoic acid
Synonyms	AKOS BBS-00002744 CHEMBRDG-BB 4400951 4-(1H-pyrazol-1-yl)benzoate 4-(1-Pyrazolyl)benzoic Acid 4-PYRAZOL-1-YL-BENZOIC ACID 4-(1H-pyrazol-1-yl)benzoic acid 4-(1H-PYRAZOL-1-YL)BENZOIC ACID Benzoic acid, 4-(pyrazol-1-yl)- benzoic acid, 4-(1H-pyrazol-1-yl)-
CAS	16209-00-0
InChI	InChI=1/C10H8N2O2/c13-10(14)8-2-4-9(5-3-8)12-7-1-6-11-12/h1-7H,(H,13,14)/p-1

4-(1H-pyrazol-1-yl)benzoic acid - Physico-chemical Properties

Molecular Formula	C10H8N2O2
Molar Mass	188.18
Density	1.28±0.1 g/cm3(Predicted)
Melting Point	269 °C
Boling Point	360.4±25.0 °C(Predicted)
Flash Point	171.8°C
Vapor Presure	8E-06mmHg at 25°C
pKa	4.01±0.10(Predicted)
Storage Condition	Sealed in dry,Room Temperature
MDL	MFCD02682056

4-(1H-pyrazol-1-yl)benzoic acid - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3
Hazard Class	IRRITANT

4-(1H-pyrazol-1-yl)benzoic acid - Introduction

4-(1H-pyrazol-1-yl)benzoic acid, chemical name is 4-(1H-pyrazol-1-yl)benzoic acid, is an organic compound. It has the following properties:

1. Appearance: 4-(1H-pyrazol-1-yl)benzoic acid is a white crystalline solid.

2. Solubility: It is insoluble in water, but soluble in organic solvents such as ethanol, methanol and dichloromethane.

3. Chemical reaction: it is a kind of acidic compounds, can participate in esterification reaction, acyl chloride reaction.

4. Stability: Under regular conditions, 4-(1H-pyrazol-1-yl)benzoic acid is relatively stable.

The main uses of this compound include:

1. Pharmaceutical field: 4-(1H-pyrazol-1-yl)benzoic acid, as a drug intermediate, can be used to prepare various drugs.

2. Materials Science: As an organic photoelectric material or photosensitive material, it has certain application value in the preparation of optoelectronic devices.

Method of preparing 4-(1H-pyrazol-1-yl)benzoic acid:

In General, 4-(1H-pyrazol-1-yl)benzoic acid can be synthesized by the following steps:

1. First, benzoic acid and 1-pyrazole carboxylic acid are condensed and reacted under appropriate solvent and temperature conditions to generate 4-(1H-pyrazol-1-yl)benzoic acid.

2. Finally, the pure 4-(1H-pyrazol-1-yl)benzoic acid product is obtained through Crystal separation and drying treatment.

Safety Information:

Regarding the safety information of 4-(1H-pyrazol-1-yl)benzoic acid, no special hazard report has been found at present. However, as a chemical substance, use should follow regular safety procedures and avoid contact with skin, eyes and respiratory system. During the operation, it is recommended to use appropriate protective measures, such as wearing protective gloves, goggles and protective masks. When storing and handling the compound, it should be kept away from fire and oxidizing agents and stored in a cool, dry and well-ventilated place.

Last Update：2024-04-09 21:54:55